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update S&R:  25 Sep06  
 

( PART 3 )


Literature References

Reference books:
  *Björntorp, P., Brodorf, B.N., OBESITY, J.B.Lippincott Company Philadelphia 1992 ISBN 0-397-50999-5
  *Eckel, R.H., OBESITY, Mechanisms and Clinical Management, Lippincott Williams & Wilkins Philadelphia 2003 ISBN 0-7817-2844-4
  *Beers MH, MD, editor-in-chief, the Merck Manual of Medical Information, Simon & Schuster Inc, Pocket Books, New York May 2004, ISBN:0-7434-7733-2
Notes (continued):
61)RCM Zhang Y, Proenca R, Maffei R, Baroni M, Leopold L,  
Friedman JM: Positional cloning of the mouse obese gene and
its human homologue, Nature. 1994,372:425-432. (Medline).
62)RCM Frederich RC, Hamann A, Anderson S, Lollmann B  ,
Lowell BB, Flier JS: Leptin levels reflect body lipid content in
mice; evidence for diet-induced resistance to leptin action.
Nature Medicine, 1995 Dec, 1(12):1311-4.
Maffei M, Halaas J, Ravussin E, Pratley RE, Lee GH, Zhang Y ,
Fei H, Kim S, Lallone R, Rangunalhan S, et al.: Leptin levels
human and Rodent measurement of plasma leptin and ob RNA
in obese and weight-reduced subjects. Nature Medicine,
1995 Nov, 1(11):1155-61.
63)RCM Recombinant Leptin (Obese Protein) and Leptin Receptor, 
Alpha Diagnostic International, www.4adi.com/fir/leptin.html
Recombinant Mouse Leptin,   www.lincoresearch.com/continue
without spaceproducts/8582.html
64)RCM Tartaglia RA, Dembski M,Weng X, Deng N, Culpeper J,  
Devos R, Richards GJ, Campfield LA, Clark FT, Deeds J, et al.,
Identification and expression cloning of a leptin receptor, OB-R.
Cell, 1995 Dec 29,83(7): 1263-71.
65)RCM Boozer CN, Leibel RL, Love RJ, Cha MC, Aronne LJ, Col. Un. 
College of Physicians and Surgeons: Synergy of sibutramine and
low-dose leptin in treatment of diet-induced obesity in rats,
Metabolism, Aug 2001, Vol 50/8; see also for an online abstract
Metabolism Table of Contents, Aug 2001  select abstract #889
For an online adapted full script see: ScienceDaily,
www.sciencedaily.com/releases/2001/10/011001072714.htm
66)RCM Halaas JL, Boozer CN, Blair-West J, Fidahusein N, Denton DA 
Friedman JM, Rockefeller University et alibi: Physiological response to long-term peripheral and central leptin infusion in lean and obese mice,
Proc Natl Acad Sci USA, Aug 1997, Vol 94/8878-83; see also:
www.pnas.org/cgi/content/full/94/16/8878 ; see also: ScienceDaily,
www.sciencedaily.com/releases/1997/08/970808054255.htm
67)A&I  Babies´ rapid weight gain linked to obesity  , Childrens Hospital Of
Philadelphia CHOP, www.chop.edu/consumer/news/story?id70164
Rapid Infant Weight Gain may predict Childhood Obesity  , ScienceDaily,
www.sciencedaily.com/releases/2001/11/011114071305.htm , or:
www.sciencedaily.com/releases/2002/02/020204074722.htm
68)A&I  Gene treatment puts block on fat cells  ,
http://news.bbc.co.uk/hi/english/health/continue without space
newsid_1731000/1731910.stm ,
BBC NEWS, selected medical headlines
69)A&I  Fat formation decoded  , Drug Discovery Online News, Jan 03, 2002
http://www.drugdiscoveryonline.com/read/nl20020103/482490 , or
http://www.drugdiscoveryonline.com/content/news/article.asp?DocID=
continue without space{00C74BE6-FD69-11D5-A789-00D0B7694F32}
70)RCM "scarsdale-support site"  ,
http://lowcarblisa.tripod.com/thescarsdalemedicaldiet/
71)RCM Un of Pittsburgh Graduate School of Public Health (GSPH),
No Association between Fertility Drugs and Ovarian Cancer etc, 
http://www.upmc.edu/newsbureau/continue without space
gsph/ness_ovarian_cancer_study.htm
ScienceDaily, No Association between Fertility Drugs and
Ovarian Ca,  http://www.sciencedaily.com/releases/continue
without space2002/01/020128080317.htm 
BBC NEWS Health Comment, Fertility drugs given cancer all-
clear http://news.bbc.co.uk/go/em/-/hi/continue without space
english/health/newsid_1782000/1782679.stm
72)RCM Purdue News, Cave men diets offer insights to today's health
problems , http://news.uns.purdue.edu/UNS/continue without
spacehtml4ever/020204.Watkins.paleo.html
73)C~U Small molecule insulin mimetics  , reduce food intake and body
weight and prevent development of obesity, Air EL, Strowski MZ,
Benoit SC, Conarello SL, Salituro GM, Xiao-Ming G, Kun L,
Woods SC, Zhang BB, Nature Medicine, Feb 2002
Vol 8, Nº 2, pp 179-183, Nature Abstract
http://www.nature.com/nmlink/v8/n2/abs/nm0202-179.html , or
BBC NEWS Health Comment, http://news.bbc.co.uk/go/without
spaceem/-/hi/english/health/newsid_1795000/1795561.stm
74)C~U Ghrelin is a growth-hormone-releasing   acylated peptide from
stomach, Kojima M, Hosoda H, Date Y, Nakazato M, Matsuo H,
Kangawa K, Nature 402, 656-660 (1999),  or Nature on line
(please register 1st) http://www.nature.com/cgi-taf/DynaPage.
cwstaf?file=/nature/journal/v402/n6762/abs/402656A0_fs.html
75)C~U Minireview: Ghrelin and the regulation of energy balance  
-A hypothalamic perspective, Horvath TL, Diano S, Sotonyi P, Heiman M,
Tschöp M, Endocrinology 142(Oct-2000) 4163-4169,  or
http://endo.endojournals.org/cgi/content/abstract/142/10/4163 .
76)C~U A role for ghrelin in the central regulation of feeding   , Nakazato M,
Murakami N, Date Y, Kojima M, Matsuo H, Kangawa K Matsukura S,
Nature 409, 194-198 (2001),  or Nature on line (please register 1st) ,
http://www.nature.com/cgi-taf/DynaPage.taf?file=/nature/journal/v409
continue without space/n6817/abs/409194A0_fs.html .
77)C~U A preprandial rise in plasma ghrelin levels suggests  a role in
meal initiation in humans, Cummings DE, Purnell JQ, Frayo RS,
Schmidova K, Wisse BE, Weigle DS, Diabetes 50(2001)
1714-1719,  or http://diabetes.diabetesjournals.org/continue
without spacecgi/content/abstract/50/8/1714 .
78)C~U Childhood Obesity and a Diabetes Epidemic,   Rocchini AP,
The New England Journal of Medicine 346,11(2002) 854-855,
or  http://content.nejm.org/cgi/content/short/346/11/854?query=TOC .
79)CMR Bypass technique evolves since first performed in 1967,  
fresnobee.com, Gastric Bypass Surgery, Dec 29, 2001,
http://www.fresnobee.com/bypass/story/1393438p-1467999c.html .
80)CMR References to Laparoscopic Gastric Bypass and associated  
topics, Center for Surgical Weight Control, San Diego Ca,
http://www.gastricbypass.com/refs.htm .
81)CMR Series of 11 color pictures presenting Roux-en-Y Gastric Bypass  
technique using a laparoscopic approach,
Schauer PR, Pittsburgh Medical Center,
http://www.laparoscopy.com/obesity/roux.html .
82)HTI  Encyclopaedia Britannica  , Vol 11:657:2b, testis/testosterone.
83)C~U Plasma Ghrelin Levels after Diet-Induced Weight Loss  
or Gastric Bypass Surgery, Cummings DE, Weigle DS, Frayo RS, et al,
The New England Journal of Medicine 346,21(May23,2002) 1623-1630,
 or http://content.nejm.org/cgi/content/short/346/21/1623?query=TOC .
831)CU Plasma Ghrelin Levels after Diet-Induced Weight Loss  
or Gastric Bypass Surgery, Cummings DE, Weigle DS, Frayo RS, et al,
The New England Journal of Medicine 346,21(May23,2002) 1623-1630,
or
http://content.nejm.org/cgi/content/short/346/21/1623?query=TOC .
84)SCG Diabetes and impaired glucose tolerance in   Aboriginal Australians:
prevalence and risk, Daniel M, Rowley KG, McDermott R, O'Dea K,
Diabetes Research and Clinical Practice 57,1 (13 June 2002) 23-33,  or
Un of N Car News Services, Aborigine study suggests body mass index
guidelines should be lower to block diabetes,
http://www.unc.edu/news/newsserv/research/daniel061102.htm .
85)C~U Elusive Ligand Ghrelin Could Have Numerous Roles   The ligand is
linked to growth hormone release, feeding regulation, energy
homeostasis, and the cardiovascular system, Kling J, The Scientist 16,12
(10 June 2002).
86)C~U Cholesterol Blocker  
http://jama.ama-assn.org/issues/v279n2/fpdf/jwm71007.pdf
http://www.vibranthealth.org/cholestatin5.htm
http://www.nutrimed.com.phyto.htm
87)RCM Leptin and SCD-1   Role for Stearoyl-CoA Desaturase-1, SCD-1
in Leptin-Mediated Weight Loss,  Cohen P, Socci ND, Tambi N,
Friedman JM, et al., Science Jul 12 2002: 240-243  or
http://www.sciencemag.org/cgi/content/full/297/5579/240/DC1
http://www.sciencedaily.com/releases/2002/07/without space
020712073745.htm or http://www.hhmi.org/news/friedman4.html
88)C~U Obesity and the Risk of Heart Failure  , Kenchaiah S, Evans JC,
Levy D, Wilson PWF, Benjamin EJ, Larson MG, Kannel WB, Vasan RS,
The New England Journal of Medicine 347,5 (Aug01,2002) 305-313,
or http://content.nejm.org/cgi/content/short/347/5/305?query=TOC ,
or NIH News Release, July 31, 2002,     NHLBI's Framingham Heart
Study finds Strong Link between Overweight/Obesity and Risk for
Heart Failure, http://www.nhlbi.nih.gov/new/press/02-07-31.htm .
89)C~U Encyclopaedia Britannica , Vol 1:618:3a, Asclepiadaceae.
90)C~U Phytopharm  
91)RCM USDA Nutrient Data Lab tables  
  http://www.nal.usda.gov/fnic/foodcomp/ .
92)RCM USDA Specific Nutrient  line search, http://www.nal.usda.
without spacegov/fnic/cgi-bin/nut_search.pl or
USDA Ranking Lists:   http://www.nal.usda.gov/without
spacefnic/foodcomp/Data/SR16/wtrank/wt_rank.html
93)RCM USDA Download USDA Nutrient Database, 30 MB  
  http://www.nal.usda.gov/fnic/foodcomp/srch/search.htm .
94)C~U Fast foods, energy density and obesity: a possible mechan-
istic link, Prentice AM, Jebb SA, Obesity Reviews (Nov,2003),
or http://www.mrc.ac.uk/txt/index/public-interest/public-press-
office/public-press_releases_2003/public-22_october_2003.htm
95)FPH Structural and molecular studies of human chorionic gonado-
  tropin and its receptor. Lustbader JW, Lobel L, Wu H, Elliott M,
  Recent Prog Horm Res., 1998; 53: 395-424, Dep. of Obst. &
  Gyn., Columbia University, NY
  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd= no space
  Retrieve&db=PubMed&list_uids=9769716&dopt=Abstract
96)FPH Molecular Structure of Gonadotropins  
  *Three-Dimensional Structure of Human Follicle-Stimulating
  Hormone, Fox KM, Dias JA, Van Roey P,  (Article discusses
  similar 3-D structure of human CG and FSH), Molecular Endo-
  crinology 15 (3): 378-389
  http://mend.endojournals.org/cgi/content/abstract/15/3/378
  *Glycoprotein hormones, Gonadotropin sequences;  A     discussion of the
  alpha subunit (generic) and the beta subunits (specific)
  http://www.chem.gla.ac.uk/protein/glyco/GPH.html
  *Glycoprotein hormones, Gonadotropin sequences;  A     discussion of the
  alpha subunit (generic) and the beta subunits (specific)
  http://www.chem.gla.ac.uk/protein/glyco/GPH.html
  *Glycoprotein hormones, alpha chain signatures;  March 1995
  http://www.chem.gla.ac.uk/protein/glyco/sig_alpha.txt
  *Glycoprotein hormones, beta chain signatures;  March 1995
  http://www.chem.gla.ac.uk/protein/glyco/sig_beta.txt
  *Maps of gonadotropin sequences, some 30 species, alpha &
  beta chains CG, LH, FSH, TSH, and receptors.
  http://www.chem.gla.ac.uk/protein/glyco/swiss.html
97)FPH Research Topic: Structure-Function Relationships among
  Gonadotropic Hormones.   Sherman GB,   Dep. of Veterinary
  Biosciences, Un. of Illinois,
  http://www.biotech.uiuc.edu/people/Sherman.html
98)C~U Merckelbach FLLM: Dr. A.T.W. Simeons, Een nieuwe genees-
  wijze van vetzucht Ch. IV,  galstenen (gall stones), ISBN 9012
  42708 7, Wetenschappelijke uitgeverij   N.V.,  Amsterdam 1971,
  Eckel RH, OBESITY,: Ch12. Hepatobiliary Complications of
  Obesity, Lippincott Williams & Wilkins Philadelphia
  2003 ISBN 0-7817-2844-4
99)C~U Festi D, cs: Anti-Aging-Guide: Un. gf G d'Annunzio Chiety, Italy
  http://www.anti-aging-guide.com/32cholecystitis.php
100)C~U Everhart JE, Contributions of Obesity and Weight Loss to
  Gallstone Disease, Annals of Internal Medicine, 119:10 1029-35
  http://www.annals.org/cgi/content/full/119/10/1029
101)C~U Weinsier RL, Wilson LJ, Lee J, "Medically safe rate of Weight
  Loss for the treatment of obesity: guideline based on risk of
  gallstone formation, Am J Med 1995 Feb;98(2):1115-117 or
  www.nutrinfo.com.ar/pagina/info/calcul0.html ( transl. at loci )
102)RCM BBC NEWS HEALTH Double surgery for obese 'safer' SAGES,
  Society of American Gastrointestinal Endoscopic Surgeons,
  Conference, http://news.bbc.co.uk/1/hi/health/3593523.stm
103)ELy Thermodynamics, Liposuction, and Metabolism,   David E.
  Kelley MD, The New England Journal of Medicine Volume 350:
  2542-2544 June17, 2004, Number25,  or
  http://content.nejm.org/cgi/content/short/350/25/2542, see
  also: Liposuction Won't Remove Fat's Health Risks, E.J.
  Mundell, http://www.klkntv.com/Global/story.asp?S=1948117
104)SCG BBC NEWS HEALTH Waistline linked to health risks
  http://news.bbc.co.uk/1/hi/health/3737064.stm
105)RCM Zelissen, P.M.J., Mathus-Vliegen, E.M.H.,: 
  Treatment of overweight and obesity in adults: proposal for a
  guideline, Ned Tijdschr Gen 2004 16 Oct 148(42) 2060--2066.
106)FPH Research Topic: hCG hormone may help prevent breast
  cancer, Fox Chase Cancer Center (Irma H. Russo, MD),
  Philadelphia. Wang R., Apr17 2005, 96th Annual Meeting Am
  Ass for Cancer Research. Or: BBC News Health 20 Apr 2005
  http://news.bbc.co.uk/1/hi/health/4460173.stm "Baby
  hormone" stops breast cancer.
107)faqFPH Beers MH, MD, editor-in-chief: the Merck Manual of
  Medical Information ISBN:0-7434-7733-2 Section 22, Ch255
  Oral Contraceptives, Simon & Schuster Inc, Pockets, New York
  May 2004.
108)C~U IDF consensus worldwide definition of the metabolic syndrom
  http://www.idf.org/webdata/docs/idf_metasyndrome_no space
  definition.pdf , also: http://www.idf.org/webdata/docs/nospace
  metabolic_syndrome_rationale.pdf, also: Beers MH, MD, editor-
  in-chief, the Merck Manual of Medical Information,d ISBN:0-
  7434-7733-2 Section 12, Disorders of Nutrition and Metabolism,
  P922, Simon & Schuster Inc, Pockets, New York, May 2004.
109)C~U Stanford scientists' discovery of hormone offers hope for
  obesity drug, http://mednews.stanford.edu/releases/2005/no
  space november/obestatin.html also:
  Obestatin, a Peptide Encoded by the Ghrelin Gene, Opposes
  Gchrelin's Effects on Food Intake, Jian V. Zhang, Pei-Gen Ren,
  O. Avsian-Kretchmer, Ching-Wei Luo, Rami Rauch, Cy Klein,
  & Aaron J. W. Hsueh, Science November 11 2005: 996-999.
110)RCM Low-dose leptin reverses skeletal muscle, autonomic, and
 neuro-endocrine adaptations to maintenance of reduced weight 
  Rosenbaum M. c.s., J. Clin. Invest. Volume 115:3579-3586
  (2005), see also: http://www.jci.org/cgi/content/abstract no
  space /115/12/3579 , or "Scientists have discovered why it is
  often harder to keep weight off than to lose it in the first place",
  http://news.bbc.co.uk/go/em/-/1/hi/health/4487690.stm,
111)RCM R.C. Atkins, MD,: Dr. Atkins New Diet Revolution, AVON
  Books ISBN:0-06-001203-X  HarperCollinsPublishers Inc, NY
  January 2002.
112)RCM A.S. Agatston, MD,: The South Beach Diet,
  ISBN:0 7553 1129 9 Headline Book Pub., a division of Hodder
  Headline, London 2003.
113)RCM Carbohydrate-restricted diets high in either monounsaturated
  fat or protein are equally effective at promoting fat loss and
  improving blood lipids, Luscombe-Marsh N.D, Noakes M,
  Wittert G.A, Keogh J.B, Foster P,  Clifton P.M.,Am J Clin Nutr
  2005 81: 762-772 (April) or:
  http://www.ajcn.org/cgi/content/abstract/81/4/762, or /full/
114)RCM Effect of an energy-restricted, high-protein, low-fat diet rel.
  to a conventional high-carbohydrate, low-fat diet on weight
  loss, body composition, nutritional status, & markers of cardio-
  vascular health in obese women, Noakes M, Keogh J.B, Foster
  P, Clifton P.M.: Am J Clin Nutr 2005 81: 1298-1306 (June) or:
  http://www.ajcn.org/cgi/content/abstract/81/6/1298, or /full/
115)RCM CSIRO Total Wellbeing Diet,: dr. M. Noakes, P.M. Clifton MD,
  ISBN:014300414X, Penguin Books Australia, May 2005.
116)HTI Cross-species analyses implicate Lipin 1 involvement in human
  glucose metabolism, Elina Suviolahti, cs, Human Molecular
  Genetics 2006 15(3):377-386; doi:10.1093/hmg/ddi448; or:
  http://hmg.oxfordjournals.org/cgi/content/abstract/15/3/377
117)RCM Phosphatidylcholine in the treatment of localized fat, Doris
  Hexsel, Marcio Serra, Rosemari Mazzuco, Taciana Dal'Forno,
  Debora Zechmeister, Journal of Drugs in Dermatology,
  Oct, 2003 or: http://www.findarticles.com/p/articles/no space
  mi_m0PDG/is_5_2/ai_110220257 (abstract)
118)C~U Encyclopaedia Britannica , Vol 17:296:table, Hormones of the
  Digestive Tract, Sa Monica classification. 1980.
119)SWR Obesity, body weight and cancer, Cancer Research UK
  http://info.cancerresearchuk.org/healthyliving/no space
  obesityandweight/  see also: "Obesity link to cancer unknown"
  http://news.bbc.co.uk/1/hi/health/5256250.stm,
120)C~U Anti-Obesity Vaccine Shows Promise, Kim Janda, Scripps
  Research Institute; http://www.ksl.com/?nid=200&sid=417689 
  see also: " 'Anti-obesity vaccine' developed"
  http://news.bbc.co.uk/1/hi/health/5232150.stm .
121)C~U Peptide YY 3-36 Reduces Food Intake, Phoenix Pharmaceut-
  icals Inc., http://www.phoenixpeptide.com/Catalog%20Files/no
  space NPY%20Section/PYY.htm .
122)C~U Inhibition of Food Intake in Obese Subjects by PYY3-36, R.L.
  Batterham, M.B. cs, The New England Journal of Medicine,
  Volume 349:941-948, Sep 4, 2003, Number10, Department of
  Metabolic Medicine, Imperial College Faculty of Medicine,
  London. http://content.nejm.org/cgi/content/no space
  full/349/10/941 or short/#/#/# ; see also: "Proof" behind high
  protein diets, http://news.bbc.co.uk/1/hi/health/5302054.stm .
123)RCM Bircher S., Mucha C.: Körperliche Aktivität und Intensität der
  höchsten Fett-oxidation bei Adipositas (English abstract)
  Physical Activity and Intensity at the max. Fat-oxidation in
  Adipose People, Erfahrungsheilkunde 8/2006, 55:441-446.
  Extensive list of references (in English) with discussion.
  see also: "Walking 'not enough to get fit' ",
  http://news.bbc.co.uk/1/hi/health/5371116.stm .
124)HTI The role of falling Leptin levels in the neuroendocrine and
  metabolic adaptation to short-term starvation in healthy men,
  Veldhuis J.D., Chan J.L., Heist K., dePaoli A.M., Mantzoros
  D.S., J. Clin. Invest. 111:1409-1421 (2003), or
  http://www.jci.org/cgi/content/full/111/9/1409 or /abstract/
  see also: http://focus.hms.harvard.edu/2003/May2_2003/no
  spaceendocrinology.html

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